Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Bromobutoxy)benzene → 1-(2-Phenoxyethyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Bromobutoxy)benzene | HCID 70986 | — |
| 반응물 | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 1-(2-Phenoxyethyl)piperazine | HCID 233187 | — |
반응 단계
The procedure of Example 2 was repeated in entirety substituting 57.0 g (0.27 moles) of 2-bromoethyl phenyl ether for 4-phenoxybutyl bromide, using 61.6 g (0.54 moles) of 1-formylpiperazine in 300 ml of 2-propanol and refluxing the mixture for 8 hours. Evaporation of the final dried chloroform extracts gave 35 g of 1-[2-phenoxyethyl]piperazine as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04562189 |
| 출처 데이터셋 | uspto-grants-1985_12 |
| ORD ID | ord-dad50e4304ca4efda3bc70ede21fbfed |
| 출처 메모 | uspto-grants-1985_12 |