Benzyl Bromide → 3-[3-(Benzyloxy)propyl]-4,5-dimethoxybenzoic acid

HRID 638915노트

반응식

HRID 638915 반응식
[OH:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[C:8]([OH:10])=[O:9].[CH2:18](Br)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([O:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[C:8]([OH:10])=[O:9])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

3

반응물 2

HCID 7498Benzyl BromideHCID 686851493-(3-Hydroxypropyl)-4,5-dimethoxybenzoic acid

생성물 1

HCID 686829003-[3-(Benzyloxy)propyl]-4,5-dimethoxybenzoic acid수율 68%

실험 절차

3-(3-Benzyloxypropyl)-4,5-dimethoxybenzoic acid was prepared from 3,4-dimethoxy-5-hydroxypropylbenzoic acid (Example 10, Step 1) and benzyl bromide in 68% yield by following Method I and used without further purification.

후처리

  1. customused without further purification

출처 및 근거

ORD 기록
ord-dc1f37d91f71437cb7c33df8e55b9e81
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07691843B2

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