Ethyl 3-chlorobenzoate → {4-[3-(3-Chloro-phenyl)-1H-pyrazol-4-yl]-pyrimidin-2-yl}-[4-(2-diethylamino-ethoxy)-phenyl]-amine

HRID 639378노트

반응식

HRID 639378 반응식
C(O[C:4](=O)[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[CH:6]=1)C.ClC1C=CC(C2[C:24]([C:25]3[CH:30]=[CH:29][N:28]=[C:27]([NH:31][C:32]4[CH:37]=[CH:36][C:35]([O:38][CH2:39][CH2:40][N:41]([CH2:44][CH3:45])[CH2:42][CH3:43])=[CH:34][CH:33]=4)[N:26]=3)=[CH:23][NH:22][N:21]=2)=CC=1>>[Cl:11][C:7]1[CH:6]=[C:5]([C:4]2[C:24]([C:25]3[CH:30]=[CH:29][N:28]=[C:27]([NH:31][C:32]4[CH:37]=[CH:36][C:35]([O:38][CH2:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45])=[CH:34][CH:33]=4)[N:26]=3)=[CH:23][NH:22][N:21]=2)[CH:10]=[CH:9][CH:8]=1

참가 물질

3

반응물 2

HCID 70785Ethyl 3-chlorobenzoateHCID 178464079HCID 178464079, 화합물

생성물 1

HCID 178464078{4-[3-(3-Chloro-phenyl)-1H-pyrazol-4-yl]-pyrimidin-2-yl}-[4-(2-diethylamino-ethoxy)-phenyl]-amine

실험 절차

The title compound is prepared as described in Example 1 using 3-chloro-benzoic acid ethyl ester (see Example 5) and 4-(2-diethylamino-ethoxy)-phenylamine (see Example 3).

출처 및 근거

ORD 기록
ord-d6707b858008419fb47b41e36bb390fc
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07691855B2

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