Methanol → HCID 10342346, 화합물

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:9][C:10]2[N:15]=[C:14]([C:16]3[C:17]([C:21]4[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:23][CH:22]=4)=[N:18][NH:19][CH:20]=3)[CH:13]=[CH:12][N:11]=2)[CH:6]=[CH:7][CH:8]=1.[CH3:31]O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:9][C:10]2[N:15]=[C:14]([C:16]3[C:17]([C:21]4[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:28])[F:29])=[CH:23][CH:22]=4)=[N:18][N:19]([CH3:31])[CH:20]=3)[CH:13]=[CH:12][N:11]=2)[CH:6]=[CH:7][CH:8]=1

참가 물질

반응물 2

HCID 887Methanol

HCID 178490981HCID 178490981, 화합물

생성물 1

HCID 10342346HCID 10342346, 화합물

실험 절차

The title compound is prepared as described in Example 55 starting from (3-methoxy-phenyl)-{4-[3-(4-trifluoromethyl-phenyl)-1H-pyrazol-4yl]-pyrimidin-2-yl}-amine (Example 87) and using methanol instead.

출처 및 근거

ORD 기록: ord-73e6d95f1e9c41ad99cd981a655f115e
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07691855B2

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