4,5-Diamino-2-phenylpyrimidine → HCID 178455651, 화합물

반응식

[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1.[C:15]([S:19]([NH:22][C@@H:23]1[CH2:28][CH2:27][C@H:26]([C:29](O)=O)[CH2:25][CH2:24]1)(=[O:21])=[O:20])([CH3:18])([CH3:17])[CH3:16]>>[C:15]([S:19]([NH:22][C@@H:23]1[CH2:24][CH2:25][C@H:26]([C:29]2[NH:8][C:7]3[C:2](=[N:3][C:4]([C:9]4[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=4)=[N:5][CH:6]=3)[N:1]=2)[CH2:27][CH2:28]1)(=[O:21])=[O:20])([CH3:18])([CH3:16])[CH3:17]

참가 물질

반응물 2

HCID 113680614,5-Diamino-2-phenylpyrimidine

HCID 178455654HCID 178455654, 화합물

생성물 1

HCID 178455651HCID 178455651, 화합물

실험 절차

By following the same procedure as described in Example 1 except that use was made of 4,5-diamino-2-phenylpyrimidine and cis-4-tert-butylsulfonylaminocyclohexanecarboxylic acid in place of 4-trifluoromethyl-1,2-phenylenediamine, the title compound was prepared.

출처 및 근거

ORD 기록: ord-3bb821e90b4048839bbb0b7d82961402
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07691860B2

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