3-Amino-1-propanol → 4-(3-Fluorophenyl)-1-[(3-hydroxypropyl)amino]-6-methoxyisoquinoline-3-carbonitrile

HRID 639901노트

반응식

HRID 639901 반응식
[F:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=3)[C:11]([NH:20][CH2:21]CO)=[N:10][C:9]=2[C:24]#[N:25])[CH:5]=[CH:6][CH:7]=1.NC[CH2:28][CH2:29][OH:30]>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=3)[C:11]([NH:20][CH2:21][CH2:28][CH2:29][OH:30])=[N:10][C:9]=2[C:24]#[N:25])[CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 90863-Amino-1-propanolHCID 114391214-(3-Fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile

생성물 1

HCID 114280864-(3-Fluorophenyl)-1-[(3-hydroxypropyl)amino]-6-methoxyisoquinoline-3-carbonitrile

실험 절차

Following the procedure for 4-(3-fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile, using 3-amino-1-propanol in place of 2-aminoethanol, the title compound was synthesized.

출처 및 근거

ORD 기록
ord-df5cfa8716394ecaa100dd4958cdace2
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07691879B2

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