HCID 11484900, 화합물 → HCID 11349161, 화합물

반응식

[OH:1][CH:2]([CH2:25][OH:26])[CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:7]([C:23]#[N:24])[N:6]=1.C(OC1C2C(=CC(OC)=CC=2)C(C2C=CC=C([F:49])C=2)=C(C#N)N=1)C=C>>[OH:1][CH:2]([CH2:25][OH:26])[CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:18]=[CH:19][CH:20]=[C:21]([F:49])[CH:22]=2)=[C:7]([C:23]#[N:24])[N:6]=1

참가 물질

반응물 2

HCID 11484900HCID 11484900, 화합물

HCID 68517560HCID 68517560, 화합물

생성물 1

HCID 11349161HCID 11349161, 화합물

실험 절차

Following the procedure for 1-(2,3-dihydroxypropoxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using 1-(allyloxy)-6-methoxy-4-(3-fluorophenyl)isoquinoline-3-carbonitrile in place of 1-(allyloxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, the title compound was synthesized.

출처 및 근거

ORD 기록: ord-1581022a115941458268c322937fab34
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07691879B2

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