Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclamate → Cyclohexylsulfamyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclamate | HCID 7533 | — |
| 반응물 | Phosphorus pentachloride | HCID 24819 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Cyclohexylsulfamyl chloride | HCID 12914615 | 82.5% |
반응 단계
Under a nitrogen atmosphere, a solution of N-cyclohexylsulfamic acid (50 g, 279 mmol) and PCl5 (58.1 g, 279 mmol) in 150 mL of toluene is very gently warmed up to 100° C. and maintained at that temperature for 1 hour. Distillation of the solution yields N-cyclohexylsulfamoyl chloride as a colorless solid (45.5 g, 82%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07691929B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-ade2508b1acf415787124703329b534f |
| 출처 메모 | uspto-grants-2010_04 |