Triethylamine → p-Ethoxalyloxyethylstyrene

HRID 6407

반응식

HRID 6407 반응식
[OH:1][CH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[CH2:9])=[CH:6][CH:5]=1.C(N(CC)CC)C.[C:19](Cl)([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[O:20]>C1C=CC=CC=1>[C:19]([O:1][CH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[CH2:9])=[CH:6][CH:5]=1)([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[O:20]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 20884Ethoxalyl chlorideHCID 220518322-(4-Vinylphenyl)ethanol

생성물 1

HCID 67847970p-Ethoxalyloxyethylstyrene

시약·촉매·용매 1

HCID 241Benzene용매

반응 조건

온도
10 °C

실험 절차

A 200 ml flask equipped with a stirrer, a thermometer and a dropping funnel was charged with 14.8 g (0.1 mol) of p-hydroxyethylstyrene, 150 ml of benzene and 10.1 g (0.1 mol) of triethylamine and cooled to 10° C. To the mixture was added dropwise with stirring 13.7 g (0.1 mol) of ethoxalyl chloride for one hour at 10° C. to precipitate a hydrochloride of triethylamine (white solid). After mixting at room temperature for 2 hours, 80 g of hexane was added to complete precipitation of the hydrochloride. The hydrochloride is removed by filteration and the resultant filtrate was condensed to obtain the aimed compound. The compound was identified by 1H NMR (360 Mz) and IR. ##STR7##

후처리

  1. customA 200 ml flask equipped with a stirrer
  2. additionTo the mixture was added dropwise
  3. customto precipitate a hydrochloride of triethylamine (white solid)
  4. addition80 g of hexane was added to complete precipitation of the hydrochloride
  5. customThe hydrochloride is removed by filteration
  6. customcondensed

출처 및 근거

ORD 기록
ord-eb42087260a94c678501a68bb3d83b03
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05248749

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