참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | Phosphorus trichloride | HCID 24387 | — |
| 반응물 | Acetic Acid N'-(3,4-Dichlorophenyl)hydrazide | HCID 612829 | — |
| 생성물 | HCID 178429550 | HCID 178429550 | 41.3% |
반응 단계
To a mixture of (V) (5.0 g, 22.8 mmol) and ethyl acetoacetate (2.97 g 22.8 mmol) was slowly added PCl3 (3.13 g, 22.8 mmol). The mixture was warmed to 50° C. for 1.5 h, poured into ice water (150 ml), and the resulting precipitate was collected on a sintered glass funnel and recrystallized from EtOH to yield (VI) (2.29 g, 41%) as white crystals, mp 208-211° C. (lit. 208-209° C.), TLC CHCl3/MeOH 9:1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07696199B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_04 |
|---|
| ORD ID | ord-2148e71d8b6f45fbae6fe90e49a94bc6 |
|---|
| 출처 메모 | uspto-grants-2010_04 |
|---|
