참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Glycolic Acid | HCID 757 | — |
| 반응물 | (+-)-3-Phenyllactic acid | HCID 3848 | — |
| 반응물 | HCID 178418581 | HCID 178418581 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Benzyl 2-hydroxyacetate | HCID 561337 | — |
반응 단계
Construction of Benzyl-glycolic Acid. Glycolic acid (7.69,100 mmols) is added to N,N'-diisopropylbenzylisourea (23.39,100 mmols) with stirring for 1 hour. The volume is then increased to 200 mL with THF, and the mixture stirred for 48 h at room temperature. After cooling the mixture to -15° C., the diisopropylurea is removed by filtration and the THF evaporated under reduced pressure. The resulting product is pumped under high vacuum for 24 h to give benzyl glycolate which may be used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05248761 |
|---|
| 출처 데이터셋 | uspto-grants-1993_09 |
|---|
| ORD ID | ord-5c317f14cf624df39c513f9852247f2b |
|---|
| 출처 메모 | uspto-grants-1993_09 |
|---|
