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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 641594생성일: 2026년 10월 26일

tert-Butyl (2-(trifluoromethyl)phenyl)carbamate → lithium 2-(7-(trifluoromethyl)-1H-indol-2-yl)acetate

https://huagongshe.com/reaction/641594

반응식

참여 물질

역할이름HCID투입량
반응물tert-Butyl (2-(trifluoromethyl)phenyl)carbamateHCID 15033883—
반응물Potassium tert-butoxideHCID 23665647—
반응물HCID 68638606HCID 68638606—
생성물lithium 2-(7-(trifluoromethyl)-1H-indol-2-yl)acetateHCID 68638559—

반응 단계

The titled compound was prepared from tert-butyl 2-(trifluoromethyl)phenylcarbamate using the procedures described in Example 26, Steps 26b through 26h, except for the use of potassium tert-butoxide instead of potassium hexamethyldisilizane in step 26g. MS (ES+) detects free acid at 244 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07696205B2
출처 데이터셋uspto-grants-2010_04
ORD IDord-0ea9e34240e14b308d76ffe5eb7ac2cc
출처 메모uspto-grants-2010_04