1,1'-Carbonyldiimidazole → HCID 178517330, 화합물

HRID 641785

반응식

HRID 641785 반응식
[NH2:1][C:2]1[C:3]([Cl:9])=[N:4][CH:5]=[CH:6][C:7]=1[NH2:8].[C:10](N1C=CN=C1)(N1C=CN=C1)=[O:11]>C1COCC1>[Cl:9][C:3]1[C:2]2[NH:1][C:10]([OH:11])=[N:8][C:7]=2[CH:6]=[CH:5][N:4]=1

참가 물질

4

반응물 2

HCID 682631,1'-CarbonyldiimidazoleHCID 2857362-Chloropyridine-3,4-diamine

생성물 1

HCID 178517330HCID 178517330, 화합물수율 86.5%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

1.1 A solution of 17.23 g of 3,4-diamino-2-chloropyridine and 19.46 g of 1,1′-carbonyldiimidazole in THF is stirred at room temperature for 16 hours. The product is separated off and dried, giving 17.6 g of 4-chloro-3H-imidazo[4,5-c]pyridin-2-ol (“1”).

후처리

  1. customThe product is separated off
  2. customdried

출처 및 근거

ORD 기록
ord-8e3e6a5471ef47f8aca17ae334117f51
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07696224B2

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