참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 1-Phenylpyrrolidine | HCID 77726 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-(Pyrrolidin-1-YL)benzenesulfonic acid | HCID 22147101 | 47.2% |
반응 단계
A solution of H2SO4 (6.8 g, 68.00 mmol) in diethylether (80 mL) was added to 1-phenylpyrrolidine (10 g, 68.03 mmol) in diethylether (20 mL) at 0° C. The diethylether was decanted, and the resulting solution was stirred for 3 hours at 170° C., then concentrated in vacuo to afford 7.3 g (43%) of 4-(pyrrolidin-1-yl)benzenesulfonic acid as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07696229B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_04 |
|---|
| ORD ID | ord-fcdcf67793a74eb0b5e9c1631abd2ed2 |
|---|
| 출처 메모 | uspto-grants-2010_04 |
|---|
