Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Ethyl Ketone → 3-(4-(3,4-Dichlorophenyl)piperazine-1-yl)propan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Ethyl Ketone | HCID 6569 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-(3,4-Dichlorophenyl)piperazine | HCID 93601 | — |
| 생성물 | 3-(4-(3,4-Dichlorophenyl)piperazine-1-yl)propan-1-ol | HCID 13097930 | — |
반응 단계
Compound 5 (0.32 mL, 3.54 mmols) was mixed with 4-(3,4-dichlorophenyl)piperazine (0.58 g, 2.5 mmols) and potassium carbonate (0.78 g, 5.6 mmols) in 15 ml 2-butanone overnight at 85° C. as described in General Procedure B to yield compound 7p and was used as is for the next reaction. MS (LC/MS, ESI): 289 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447122B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-b2b44e96151540e98a8efe67154bbde0 |
| 출처 메모 | uspto-grants-2016_09 |