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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 642227생성일: 2026년 10월 26일

Ethyl 2-((tert-butoxycarbonyl)amino)acetate → 4-Bromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642227

반응식

참여 물질

역할이름HCID투입량
반응물Ethyl 2-((tert-butoxycarbonyl)amino)acetateHCID 357729—
반응물4-Bromo-2-bromomethyl-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68428064—
생성물4-Bromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68428323—

반응 단계

Prepared in analogy to that of Example 1(c) from 4-bromo-2-bromomethyl-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 643 (M+Na+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07696223B2
출처 데이터셋uspto-grants-2010_04
ORD IDord-d3bc6137fd3841a8bfeb39681fce6b7b
출처 메모uspto-grants-2010_04