Ethyl 1,2-dimethyl-1H-pyrrole-3-carboxylate → 4,5-Dibromo-2-bromomethyl-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

HRID 642247노트

반응식

HRID 642247 반응식
[CH2:1]([O:3][C:4]([C:6]1[C:10]([Br:11])=[C:9]([Br:12])[N:8]([C:13]2C=CC=CC=2)[C:7]=1[CH2:19][Br:20])=[O:5])[CH3:2].C(OC(C1C=CN(C)C=1C)=O)C>>[CH2:1]([O:3][C:4]([C:6]1[C:10]([Br:11])=[C:9]([Br:12])[N:8]([CH3:13])[C:7]=1[CH2:19][Br:20])=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 12211514Ethyl 1,2-dimethyl-1H-pyrrole-3-carboxylateHCID 684265314,5-dibromo-2-bromomethyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester

생성물 1

HCID 684265464,5-Dibromo-2-bromomethyl-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

실험 절차

Prepared in analogy to that of 4,5-dibromo-2-bromomethyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester from 1,2-Dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester; the title product, 1H NMR (200 MHz, CDCl3): δ (ppm)=4.93 (s, 2H), 4.34 (q, 2H, J=7.1 Hz), 3.69 (s, 3H), 1.40 (t, 3H, J=7.1 Hz).

출처 및 근거

ORD 기록
ord-f267570b36c94d6db6c235281f777812
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07696223B2

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