N-Methylethylamine → HCID 58900226, 화합물

반응식

[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]1[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=[CH:14][CH:13]=1)[C:6]1[C:22](=[O:27])[O:23][C:24](=[O:26])[CH2:25][C:5]2=1.[CH2:28]([NH:30][CH3:31])[CH3:29]>>[CH2:28]([N:30]([CH3:31])[C:24]([CH2:25][C:5]1[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=2)[N:7]([CH2:11][C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=[CH:14][CH:13]=2)[C:6]=1[C:22]([OH:23])=[O:27])=[O:26])[CH3:29]

참가 물질

반응물 2

HCID 12219N-Methylethylamine

HCID 86613188HCID 86613188, 화합물

생성물 1

HCID 58900226HCID 58900226, 화합물

실험 절차

6-Fluoro-9-naphthalen-1-ylmethyl-4,9-dihydro-pyrano[3,4-b]indole-1,3-dione (from Example 68.1.) was ring opened with ethylmethylamine at 22° C. to give the title compound as a white solid. MS: 417.3 ([M−H]−).

출처 및 근거

ORD 기록: ord-664721e6b50f454287d9ab7fc678dfb6
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07696240B2

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