참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosphorus tribromide | HCID 24614 | — |
| 반응물 | 2-Chloro-4-(hydroxymethyl)-3-methylbenzonitrile | HCID 68577571 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(Bromomethyl)-2-chloro-3-methylbenzonitrile | HCID 68577413 | — |
반응 단계
To a solution of compound 7B (700 mg, 3.9 mmol) in CH2Cl2 (15 mL) was added PBr3 (5.8 mL, 5.8 mmol, 1N in CH2Cl2) at −15° C., and stirred at −15° C. for 3 hr. The reaction was slowly quenched with saturated NaHCO3 solution at −15° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07696241B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_04 |
|---|
| ORD ID | ord-a46c7acaaea94ee58f98a39797973cdf |
|---|
| 출처 메모 | uspto-grants-2010_04 |
|---|
