Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(1-Benzylpiperidin-4-yl)morpholine → 4-Morpholinopiperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(1-Benzylpiperidin-4-yl)morpholine | HCID 783831 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-Morpholinopiperidine | HCID 795724 | — |
반응 단계
41.59 g (0.16 Mol) 4-[1-(phenylmethyl)-4-piperidinyl]-morpholine (N) are dissolved in 400 mL methanol, combined with 5.2 g palladium on activated charcoal (10%) and hydrogenated for 18 hours at ambient temperature with 50 psi hydrogen. The catalyst is filtered off and the filtrate is evaporated down. A colourless oil remains, which crystallises after a short time.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07696346B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-002e7a9350934f3ca9561e62fd89d388 |
| 출처 메모 | uspto-grants-2010_04 |