Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 9-Methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one | HCID 598875 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one | HCID 11790505 | — |
반응 단계
Accordingly, 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one was synthesized from 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one using a formaldehyde reagent (paraformaldehyde) and a mineral acid (HCl) in an aprotic solvent (DMF). Note that this reaction was rapid and high yielding, even though it was performed without using glacial acetic acid as a solvent, and without using a secondary amine as a catalyst.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07696356B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-1aef5c842c6b48729cb0ba28b1f33527 |
| 출처 메모 | uspto-grants-2010_04 |