5-Hexynoic acid → 6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid

참여 물질

역할	이름	HCID	투입량
반응물	5-Hexynoic acid	HCID 143036	—
반응물	N-(2-hydroxy-1-methyl-ethyl)-3-iodobenzamide	HCID 23730076	—
생성물	6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid	HCID 11358215	99%

The iodobenzamide (1)(2.00 g, 6.5 mmol) was coupled with 5-hexynoic acid using method B giving product (4)(1.87 g, 6.42 mmol; 99% yield).