Potassium Carbonate → HCID 68578970, 화합물
반응식
Br[C:2]1[C:7]([N:8]2[CH2:13][CH2:12][O:11]CC2)=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:14]1[CH:19]=[C:18](B(O)O)[CH:17]=[N:16][CH:15]=1.C([O-])([O-])=O.[K+].[K+]>Cl[Pd]Cl.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.[Fe+2]>[N:14]1[CH:19]=[C:18]([C:5]2[CH:4]=[CH:3][C:2]3[O:11][CH2:12][CH2:13][NH:8][C:7]=3[CH:6]=2)[CH:17]=[N:16][CH:15]=1참가 물질
6
실험 절차
In a manner similar to those previously described (Examples 15-17, 67), 6-bromophenyl morpholine (67C) was treated with pyrimidine-5-boronic acid, PdCl2(dppf, and K2CO3, to provide compound 6-(pyrimidin-5-yl)-benzomorpholine, which was further converted to the title compound 68. MS m/z 294 (MH+).
출처 및 근거
- ORD 기록
- ord-8555efbca531467bae767978bf074fc3
- 출처 데이터셋
- uspto-grants-2010_04
- 특허 번호
- US07700592B2
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