Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Dimethylaminomethylene-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one → 3-(4,5-Dihydro-2-oxa-1,3,7,9-tetraaza-cyclopenta[a]naphthalen-8-ylamino)-phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Dimethylaminomethylene-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one | HCID 67405521 | — |
| 반응물 | HCID 178418735 | HCID 178418735 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(4,5-Dihydro-2-oxa-1,3,7,9-tetraaza-cyclopenta[a]naphthalen-8-ylamino)-phenol | HCID 11403271 | — |
반응 단계
The DMF solution of 5-dimethylaminomethylene-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one 0.1 g (0.00052 mol) and 3 equivalents of N-(3-hydroxy-phenyl)-guanidine was stirred at 110° C. for overnight, the final product was purified by directly injecting the DMF reaction solution into prep HPLC.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07700609B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-73c974636d2d496694434067cb7f9f55 |
| 출처 메모 | uspto-grants-2010_04 |