Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hexane → N-(4-tert-Butylphenyl)-N'-[2-(1H-indol-2-yl)phenyl]urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | 2-(2-Aminophenyl)indole | HCID 735966 | — |
| 반응물 | 1-Tert-butyl-4-isocyanatobenzene | HCID 2735695 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(4-tert-Butylphenyl)-N'-[2-(1H-indol-2-yl)phenyl]urea | HCID 16092112 | — |
반응 단계
To a solution of commercially available 2-(1H-indol-2-yl)benzenamine (62 mg, 0.3 mmol) in dichloromethane (1.5 mL) at rt was added 4-tert-butylphenyl isocyanate (30 mg, 0.171 mmol). The reaction was stirred overnight at rt. Hexane (1 mL) was added to the reaction mixture and the reaction was allowed to set for ˜5 min. Example 1 was the solid formed which was collected by filtration (47.3 mg). (M+H)+=384.37.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07700620B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-f708b8748d114bc9b9f41b1b12c4132f |
| 출처 메모 | uspto-grants-2010_04 |