Methyl 4-fluoro-2-(3-tert-butoxycarbonylaminopropoxy)benzoate → 4-Fluoro-2-(3-tert-butoxycarbonylaminopropoxy)benzoic acid

HRID 644222노트

반응식

HRID 644222 반응식
FC1C=CC(C(O)=O)=C(OCCC(N=C=O)OC(C)(C)C)C=1.[F:23][C:24]1[CH:33]=[CH:32][C:27]([C:28]([O:30]C)=[O:29])=[C:26]([O:34][CH2:35][CH2:36][CH2:37][NH:38][C:39]([O:41][C:42]([CH3:45])([CH3:44])[CH3:43])=[O:40])[CH:25]=1>>[F:23][C:24]1[CH:33]=[CH:32][C:27]([C:28]([OH:30])=[O:29])=[C:26]([O:34][CH2:35][CH2:36][CH2:37][NH:38][C:39]([O:41][C:42]([CH3:45])([CH3:44])[CH3:43])=[O:40])[CH:25]=1

참가 물질

3

반응물 2

HCID 57602453Methyl 4-fluoro-2-(3-tert-butoxycarbonylaminopropoxy)benzoateHCID 866342074-Fluoro-2-(3-tert-butoxy-carbonylaminopropoxy)benzoic acid

생성물 1

HCID 685326094-Fluoro-2-(3-tert-butoxycarbonylaminopropoxy)benzoic acid

실험 절차

Using a procedure analogous to Example 21-D, 4-fluoro-2-(3-tert-butoxy-carbonylaminopropoxy)benzoic acid was prepared from methyl 4-fluoro-2-(3-tert-butoxycarbonylaminopropoxy)benzoate.

출처 및 근거

ORD 기록
ord-d1a6a67a894949e4a23883b74bccf2c3
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07700628B2

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