1,3-Dimethyl-1H-pyrazol-5-amine → N-(1,3-Dimethylpyrazol-4-yl)-5-fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]benzamide

반응식

Cl.[CH3:2][N:3]1[CH:7]=[C:6]([NH:8][C:9](=[O:39])[C:10]2[CH:15]=[C:14]([F:16])[CH:13]=[CH:12][C:11]=2[NH:17][C:18](=[O:38])[C:19]2[CH:24]=[CH:23][C:22]([N:25]3[CH2:29][CH2:28][CH2:27][CH2:26]3)=[CH:21][C:20]=2[O:30][CH:31]2[CH2:36][CH2:35][N:34]([CH3:37])[CH2:33][CH2:32]2)[C:5]([CH3:40])=[N:4]1.FC1C=CC2N=C(C3C=CC(N4CCCC4)=CC=3OC3CCN(C)CC3)OC(=O)C=2C=1.NC1N(C)N=C(C)C=1>>[CH3:2][N:3]1[CH:7]=[C:6]([NH:8][C:9](=[O:39])[C:10]2[CH:15]=[C:14]([F:16])[CH:13]=[CH:12][C:11]=2[NH:17][C:18](=[O:38])[C:19]2[CH:24]=[CH:23][C:22]([N:25]3[CH2:26][CH2:27][CH2:28][CH2:29]3)=[CH:21][C:20]=2[O:30][CH:31]2[CH2:36][CH2:35][N:34]([CH3:37])[CH2:33][CH2:32]2)[C:5]([CH3:40])=[N:4]1