4-Methoxy-2-naphthylamine → 2-Acetoxy-5-chloro-N-(1-methoxynaphthalen-3-yl)benzamide

반응식

[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[CH3:15][O:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[C:19]([NH2:27])[CH:18]=1>>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([NH:27][C:19]1[CH:18]=[C:17]([O:16][CH3:15])[C:26]2[C:21]([CH:20]=1)=[CH:22][CH:23]=[CH:24][CH:25]=2)=[O:9])(=[O:3])[CH3:2]

참가 물질

반응물 2

HCID 1510414-Methoxy-2-naphthylamine

HCID 28208132-(Acetyloxy)-5-chlorobenzoic acid

생성물 1

HCID 99763872-Acetoxy-5-chloro-N-(1-methoxynaphthalen-3-yl)benzamide수율 39.9%

실험 절차

Using 2-acetoxy-5-chlorobenzoic acid and 4-methoxy-2-naphthylamine as the raw materials, the same operation as the Example 24 gave the title compound.

출처 및 근거

ORD 기록: ord-6ec35c6595814f46ab8f2ae0cf734010
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07700655B2

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