5-Chlorosalicylic Acid → HCID 86602680, 화합물

반응식

[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([C:22]#[N:23])=[C:16]([C:18]([CH3:21])([CH3:20])[CH3:19])[N:17]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([C:22]#[N:23])=[C:16]([C:18]([CH3:19])([CH3:21])[CH3:20])[N:17]=1)=[O:9]

참가 물질

반응물 2

HCID 94475-Chlorosalicylic Acid

HCID 27685182-amino-4-(tert-butyl)-1,3-thiazole-5-carbonitrile

생성물 1

HCID 86602680HCID 86602680, 화합물수율 63.4%

실험 절차

Using 5-chlorosalicylic acid and 2-amino-5-cyano-4-[(1,1-dimethyl)-ethyl]thiazole as the raw materials, the same operation as the Example 16 gave the title compound.

출처 및 근거

ORD 기록: ord-c6bf21f16fa542a79041fd89a5b4c8f3
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07700655B2

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