4-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)aniline → 2-Acetoxy-N-{4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl}-4-chlorobenzamide

HRID 644490

반응식

HRID 644490 반응식
[C:1]([O:4][C:5]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH2:15][C:16]1[CH:21]=[CH:20][C:19]([N:22]2[C:26]([C:27]([F:30])([F:29])[F:28])=[CH:25][C:24]([C:31]([F:34])([F:33])[F:32])=[N:23]2)=[CH:18][CH:17]=1>>[C:1]([O:4][C:5]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:6]=1[C:7]([NH:15][C:16]1[CH:17]=[CH:18][C:19]([N:22]2[C:26]([C:27]([F:28])([F:29])[F:30])=[CH:25][C:24]([C:31]([F:34])([F:33])[F:32])=[N:23]2)=[CH:20][CH:21]=1)=[O:9])(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 27406684-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)anilineHCID 15278256HCID 15278256, 화합물

생성물 1

HCID 230699732-Acetoxy-N-{4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl}-4-chlorobenzamide수율 74%

실험 절차

Using 2-acetoxy-4-chlorobenzoic acid and 1-(4-aminophenyl)-3,5-bis(trifluoromethyl)pyrazole as the raw materials, the same operation as the Example 24 gave the title compound.

출처 및 근거

ORD 기록
ord-e7b96b4d6c6d40e99dcd0632486e7b7c
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07700655B2

연결된 노트

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