5-Chlorosalicylic Acid → HCID 68578895, 화합물

반응식

[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]2[C:23]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[CH:22][C:21]([C:30]([F:33])([F:32])[F:31])=[N:20]2)=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]2[C:23]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[CH:22][C:21]([C:30]([F:33])([F:32])[F:31])=[N:20]2)=[CH:15][CH:14]=1)=[O:9]

참가 물질

반응물 2

HCID 94475-Chlorosalicylic Acid

HCID 230699634-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)aniline

생성물 1

HCID 68578895HCID 68578895, 화합물수율 73.2%

실험 절차

Using 5-chlorosalicylic acid and 1-(4-aminophenyl)-5-phenyl-3-(trifluoromethyl)pyrazole as the raw materials, the same operation as the Example 16 gave the title compound.

출처 및 근거

ORD 기록: ord-dcae818b293d497aa25da6c89ecf412b
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07700655B2

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