1-(4-Methylpiperazin-1-yl)-3-(3-phenyl-6-trifluoromethyl-3H-benzimidazol-4-yl)prop-2-en-1-one → HCID 67485635, 화합물
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C[O:2]C(=O)C=CC1C2N(C3C=CC=CC=3)C(C(F)(F)F)=NC=2C=CC=1.CN1[CH2:32][CH2:31][N:30]([C:33](=[O:55])[CH:34]=[CH:35][C:36]2[C:44]3[N:43]([C:45]4[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=4)[CH:42]=[N:41][C:40]=3[CH:39]=[C:38]([C:51]([F:54])([F:53])[F:52])[CH:37]=2)[CH2:29][CH2:28]1>>[N:30]1([C:33](=[O:55])[CH:34]=[CH:35][C:36]2[C:44]3[N:43]([C:45]4[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=4)[CH:42]=[N:41][C:40]=3[CH:39]=[C:38]([C:51]([F:53])([F:54])[F:52])[CH:37]=2)[CH2:31][CH2:32][O:2][CH2:28][CH2:29]1참가 물질
3
실험 절차
This was prepared from 3-(3-phenyl-trifluoromethyl-3H-benzimidazol-4-yl)acrylic acid methyl ester in a similar manner to 1-(4-methylpiperazin-1-yl)-3-(3-phenyl-6-trifluoromethyl-3H-benzimidazol-4-yl)prop-2-en-1-one to afford the title compound as a white solid (350 mg, 60%), m/z 402.2 (M+H)+.
출처 및 근거
- ORD 기록
- ord-8c61a770602a442eae4eed8d021d9144
- 출처 데이터셋
- uspto-grants-2010_04