1-[3-(tert-Butyldimethylsilanyloxy)phenyl]propan-1-ol → 1-[3-(tert-Butyldimethylsilanyloxy)phenyl]propan-1-one

HRID 644569노트

반응식

HRID 644569 반응식
[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]([OH:18])[CH2:16][CH3:17])[CH:12]=[CH:13][CH:14]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]>[O-2].[O-2].[Mn+4]>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([C:15](=[O:18])[CH2:16][CH3:17])[CH:12]=[CH:13][CH:14]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

참가 물질

3

반응물 1

HCID 685795511-[3-(tert-Butyldimethylsilanyloxy)phenyl]propan-1-ol

생성물 1

HCID 150499531-[3-(tert-Butyldimethylsilanyloxy)phenyl]propan-1-one

시약·촉매·용매 1

HCID 178418406HCID 178418406, 화합물촉매

실험 절차

In a manner analogous to example 1j, by reaction of 45 g (0.17 mol) of 1-[3-(tert-butyldimethylsilanyloxy)phenyl]propan-1-ol with (148 g, 1.7 mol) of manganese dioxide. A yellow oil is obtained (m=45 g, Y=100%).

후처리

  1. customA yellow oil is obtained (m=45 g, Y=100%)

출처 및 근거

ORD 기록
ord-51472ba040744b56ad5abf194f59e5cb
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07700657B2

반응 노트

불러오는 중…