Succinic Acid → Succinic acid, di(2-octyl) ester

HRID 64504

반응식

HRID 64504 반응식
[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH3:9][CH:10](O)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].CS(O)(=O)=O>C1(C)C=CC=CC=1>[CH3:9][CH:10]([O:5][C:4](=[O:6])[CH2:3][CH2:2][C:1]([O:8][CH:10]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:9])=[O:7])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

5

반응물 3

HCID 1110Succinic AcidHCID 6395Methanesulfonic AcidHCID 200832-Octanol

생성물 1

HCID 85861366Succinic acid, di(2-octyl) ester

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A mixture of succinic acid (Alfa-Aesar, 149.00 g, 1.26 mol), 2-octanol (Alfa-Aesar, 350.00 g, 2.69 mol), toluene (625 mL), and methanesulfonic acid (Alfa-Aesar, 2.00 g, 21 mmol) was heated to reflux for 6 hours. The water liberated was collected in a Dean Stark trap. The mixture was cooled, washed with saturated sodium bicarbonate (300 mL) and brine (100 mL), and dried over magnesium sulfate. The solvent was removed under vacuum to give a yellow oil that was used without further purification (426.39 g).

후처리

  1. temperaturewas heated
  2. temperatureto reflux for 6 hours
  3. customThe water liberated was collected in a Dean Stark trap
  4. temperatureThe mixture was cooled
  5. washwashed with saturated sodium bicarbonate (300 mL) and brine (100 mL)
  6. dry with materialdried over magnesium sulfate
  7. customThe solvent was removed under vacuum
  8. customto give a yellow oil that
  9. customwas used without further purification (426.39 g)

출처 및 근거

ORD 기록
ord-d9a54e4d69f34c5d96fd25a0d6324924
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09447309B2

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