Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Phosphate, Tribasic → N-(1,1':4',1''-terphenyl-3-yl)indolo[2,3-a]carbazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Phosphate, Tribasic | HCID 62657 | — |
| 반응물 | 1-Bromo-3-(4-phenylphenyl)benzene | HCID 15329710 | — |
| 반응물 | Indolo[2,3-a]carbazole | HCID 21882147 | — |
| 촉매 | Tris(1,1-dimethylethyl)phosphine | HCID 83681 | — |
| 촉매 | Tris(dibenzylideneacetone) dipalladium | HCID 9832798 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-(1,1':4',1''-terphenyl-3-yl)indolo[2,3-a]carbazole | HCID 68089261 | 67.5% |
반응 단계
Indolo[2,3-a]carbazole (9.8 g) was dissolved in 150 ml of dry toluene under nitrogen. 12.9 g of 3-bromo-p-terphenyl, 0.65 g of tris(dibenzylideneacetone) dipalladium, 0.46 g of tri-t-butylphosphine and 40.3 g of potassium orthophosphate were added and heated to reflux for 16 h. After the completion of reaction, the reaction was quenched with water. The reaction mixture was then extracted using ethyl acetate; and the organic layer was dried over anhydrous sodium sulfate and evaporated to dryness under vacuum. Subsequent silica gel column chromatography using ethyl acetate/hexane (1:9) as eluent, yielded 12.6 g of N-(1,1′:4′,1″-terphenyl-3-yl)indolo[2,3-a]carbazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09450192B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-b1a99e4574d64a38801f876484d345f0 |
| 출처 메모 | uspto-grants-2016_09 |