Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloronicotinonitrile → 2-(2-Phenoxy-phenyl)nicotinonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloronicotinonitrile | HCID 81079 | — |
| 반응물 | (2-Phenoxyphenyl)boronic acid | HCID 2773559 | — |
| 생성물 | 2-(2-Phenoxy-phenyl)nicotinonitrile | HCID 39736277 | 50% |
반응 단계
Prepared in 50% yield from 2-chloro-3-cyanopyridine and 2-phenoxyphenylboronic acid according to the procedure described for Example 153A. MS (ESI−) m/z 273.0 (M+H)+; 1H NMR (CDCl3) δ 6.94 (d, J=7.1 Hz, 1H), 7.06-7.11 (m, 3H), 7.20-7.44 (m, 5H), 7.54 (dd, J=7.5, 1.7 Hz, 1H), 8.00 (dd, J=8.1, 2.0 Hz, 1H), 8.86 (dd, J=5.1, 1.7 Hz, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07704997B1 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-60ccbd3326da45d0951e5803d2989966 |
| 출처 메모 | uspto-grants-2010_04 |