Chloroacetyl chloride → N-methoxy-N-methyl-2-piperazin-1-yl-acetamide dihydrochloride

HRID 645765

반응식

HRID 645765 반응식
[C:1]([O:5]C(N1CCNCC1)=O)(C)(C)C.[Cl:14]CC(Cl)=O.CONC.[ClH:23].Cl.COC[CH:28]([NH:30][C:31](=[O:39])[CH2:32][N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)C>>[ClH:14].[ClH:23].[CH3:1][O:5][N:30]([CH3:28])[C:31](=[O:39])[CH2:32][N:33]1[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]1

참가 물질

5

반응물 4

HCID 6577Chloroacetyl chlorideHCID 14232N,O-DimethylhydroxylamineHCID 143452tert-Butyl piperazine-1-carboxylateHCID 67245894N-(2-methoxy-1-methylethyl)-2-piperazin-1-yl-acetamide dihydrochloride

생성물 1

HCID 86613637N-methoxy-N-methyl-2-piperazin-1-yl-acetamide dihydrochloride

실험 절차

N-Methoxy-N-methyl-2-piperazin-1-yl-acetamide dihydrochloride was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N-methoxy-N-methylamine in an analogous manner as described for the preparation of N-(2-methoxy-1-methyl-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride (example 40).

출처 및 근거

ORD 기록
ord-2f4faab9eaa54b9b96f7b431e40b78ab
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07705007B2

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