Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → N,N-diethyl-2-[4-(quinoxalinyloxy)phenoxy]propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2-{4-[(Quinoxalin-2-yl)oxy]phenoxy}propanoic acid | HCID 13670531 | — |
| 용매 | Butyl Chloride | HCID 8005 | — |
| 생성물 | N,N-diethyl-2-[4-(quinoxalinyloxy)phenoxy]propanamide | HCID 13670533 | — |
반응 단계
The title compound can be prepared by interaction of 2-[4-(2-quinoxalinyloxy)phenoxy]propionic acid with thionyl chloride in a suitable solvent such as chlorobutane. Add a solution of 3.3 g (0.01 mole) 2-[4-(2-quinoxalinyloxy)phenoxy]propionyl chloride in 30 cc methylene chloride to a cold (5° C.) solution of 1.8 g (0.025 mole) diethylamine in 30 cc methylene chloride. Stir the mixture at room temperature overnight. Wash the methylene chloride solution with water and dry over magnesium sulfate. Remove the methylene chloride under vacuum to yield N,N-diethyl-2-[4-(quinoxalinyloxy)phenoxy]propanamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04609396 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-eba8ecdf45e04ad4a95d712d12116c4e |
| 출처 메모 | uspto-grants-1986_09 |