4-Bromo-2-nitrotoluene → 5-(4-Tert-butylphenyl)-1-(4-methyl-3-nitrophenyl)indole-2-carboxylic acid

반응식

C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([C:15]1[CH:20]=[CH:19][C:18]([C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:17][CH:16]=1)=[CH:10][CH:9]=2)=[O:5])C.Br[C:26]1[CH:31]=[CH:30][C:29]([CH3:32])=[C:28]([N+:33]([O-:35])=[O:34])[CH:27]=1>>[C:21]([C:18]1[CH:19]=[CH:20][C:15]([C:11]2[CH:12]=[C:13]3[C:8](=[CH:9][CH:10]=2)[N:7]([C:26]2[CH:31]=[CH:30][C:29]([CH3:32])=[C:28]([N+:33]([O-:35])=[O:34])[CH:27]=2)[C:6]([C:4]([OH:3])=[O:5])=[CH:14]3)=[CH:16][CH:17]=1)([CH3:22])([CH3:24])[CH3:23]

참가 물질

반응물 2

HCID 1235464-Bromo-2-nitrotoluene

HCID 68475095Ethyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylate

생성물 1

HCID 686984005-(4-Tert-butylphenyl)-1-(4-methyl-3-nitrophenyl)indole-2-carboxylic acid

실험 절차

The title compound was prepared in accordance with Example 1 using 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester and 4-bromo-1-methyl-2-nitrobenzene.

출처 및 근거

ORD 기록: ord-4491f1bc8029478eb4a25ff04eebd124
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07705023B2

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