1-Bromo-4-cyclopropoxybenzene → 5-(4-tert-Butylphenyl)-1-(4-cyclopropoxyphenyl)-1H-indole-2-carboxylic acid ethyl ester

HRID 646151노트

반응식

HRID 646151 반응식
[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([C:15]1[CH:20]=[CH:19][C:18]([C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:17][CH:16]=1)=[CH:10][CH:9]=2)=[O:5])[CH3:2].Br[C:26]1[CH:31]=[CH:30][C:29]([O:32][CH:33]2[CH2:35][CH2:34]2)=[CH:28][CH:27]=1>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([C:26]2[CH:31]=[CH:30][C:29]([O:32][CH:33]3[CH2:35][CH2:34]3)=[CH:28][CH:27]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([C:15]1[CH:16]=[CH:17][C:18]([C:21]([CH3:23])([CH3:22])[CH3:24])=[CH:19][CH:20]=1)=[CH:10][CH:9]=2)=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 509986941-Bromo-4-cyclopropoxybenzeneHCID 68475095Ethyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylate

생성물 1

HCID 686973605-(4-tert-Butylphenyl)-1-(4-cyclopropoxyphenyl)-1H-indole-2-carboxylic acid ethyl ester

실험 절차

The sub-title compound was prepared in accordance with Example 1(b) from 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester (see Example 1(a)) and 1-bromo-4-cyclopropoxybenzene (see step (c) above).

출처 및 근거

ORD 기록
ord-1911e2ce3b614c8ea623b5329237f8bc
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07705023B2

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