4-Cyclohexylbenzeneboronic acid → HCID 68698624, 화합물

반응식

C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([C:14]=1[Cl:15])=[CH:12][C:11](Br)=[CH:10][CH:9]=2)=[O:5])C.[CH:17]1([C:23]2[CH:28]=[CH:27][C:26](B(O)O)=[CH:25][CH:24]=2)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>>[Cl:15][C:14]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:20]3[CH:19]=[CH:18][C:17]([CH:23]4[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]4)=[CH:22][CH:21]=3)[CH:12]=2)[NH:7][C:6]=1[C:4]([OH:3])=[O:5]

참가 물질

반응물 2

HCID 45891894-Cyclohexylbenzeneboronic acid

HCID 28330549ethyl 5-bromo-3-chloro-1H-indole-2-carboxylate

생성물 1

HCID 68698624HCID 68698624, 화합물

실험 절차

The sub-title compound was prepared in accordance with Example 1(a) from 5-bromo-3-chloroindole-2-carboxylic acid ethyl ester (see Example 35, Method 1, step (a)) and 4-cyclohexylphenylboronic acid.

출처 및 근거

ORD 기록: ord-9c9a59524fcd4706b26574ab4e384cf8
출처 데이터셋: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07705023B2

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