2,5-Dibromopyrimidine → HCID 68700384, 화합물

HRID 646162노트

반응식

HRID 646162 반응식
[CH2:1]([O:3][C:4]([C:6]1[N:7]([C:24]2[CH:29]=[CH:28][C:27]([O:30][CH:31]3[CH2:35][CH2:34][CH2:33][CH2:32]3)=[CH:26][CH:25]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][C:11](B1OC(C)(C)C(C)(C)O1)=[CH:10][CH:9]=2)=[O:5])[CH3:2].Br[C:37]1[N:42]=[CH:41][C:40]([Br:43])=[CH:39][N:38]=1>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([C:24]2[CH:25]=[CH:26][C:27]([O:30][CH:31]3[CH2:35][CH2:34][CH2:33][CH2:32]3)=[CH:28][CH:29]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([C:37]1[N:42]=[CH:41][C:40]([Br:43])=[CH:39][N:38]=1)=[CH:10][CH:9]=2)=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 109555882,5-DibromopyrimidineHCID 68696805HCID 68696805, 화합물

생성물 1

HCID 68700384HCID 68700384, 화합물

실험 절차

The sub-title compound was prepared in accordance with Example 8(b), from 1-(4-cyclopentoxyphenyl)-5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester (see step (d) above) and 2,5-dibromopyrimidine (see step (f) above).

출처 및 근거

ORD 기록
ord-c5c9de2197264f1aa09a35054c1251cd
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07705023B2

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