Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methylpiperidine → 1-(5-Chloro-2-nitro-phenyl)-4-methyl-piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methylpiperidine | HCID 69381 | — |
| 반응물 | 4-Chloro-2-fluoro-1-nitrobenzene | HCID 69691 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(5-Chloro-2-nitro-phenyl)-4-methyl-piperidine | HCID 58638501 | 99.1% |
반응 단계
The procedure of Example 4, step (a) was followed using 0.950 g (5.43 mmol) of 4-chloro-2-fluoronitrobenzene and 1.93 mL (16.3 mmol) of 4-methylpiperidine in 10 mL of EtOH to afford 1.37 g (99%) of the title compound as an orange oil which crystallized on standing: Mass spectrum (ESI, m/z): Calcd. for C12H15ClN2O2, 255.1 (M+H), found 255.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07705042B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-753252e58d0c4122b412b699fcd85a87 |
| 출처 메모 | uspto-grants-2010_04 |