Sulfuric Acid → HCID 5360149, 화합물

HRID 647228노트

반응식

HRID 647228 반응식
S(=O)(=O)(O)O.S([O:16][C:17]1[C:22]([NH:23]S(C2C=CC(C)=CC=2)(=O)=O)=[CH:21][C:20]([CH3:34])=[C:19]([N+:35]([O-:37])=[O:36])[CH:18]=1)(C1C=CC(C)=CC=1)(=O)=O>O>[NH2:23][C:22]1[C:17]([OH:16])=[CH:18][C:19]([N+:35]([O-:37])=[O:36])=[C:20]([CH3:34])[CH:21]=1

참가 물질

4

반응물 2

HCID 1118Sulfuric AcidHCID 131713131HCID 131713131, 화합물

생성물 1

HCID 5360149HCID 5360149, 화합물수율 85%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To 120 ml of stirring concentrated sulfuric acid at room temperature was added 12.0 g (0.0252 mol) of 5-nitro-2-p-toluenesulfonamido-p-cresol tosylate. Complete solution occurred without exotherm in 15 minutes. After stirring 11/2 hours the reaction was poured into 1500 ml of water and extracted with ethyl acetate. The organic layer was washed with aqueous sodium carbonate, dried over magnesium sulfate and concentrated under reduced pressure to yield 3.6 g (85 percent) of pure product as an orange solid.

후처리

  1. extractionextracted with ethyl acetate
  2. washThe organic layer was washed with aqueous sodium carbonate
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-281e760d139d42a58073146e52ae3d8f
출처 데이터셋
uspto-grants-1983_10
특허 번호
US04407930

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