Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 4-[4-(2-Chloro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-[2-Chloro-4-(trifluoromethyl)phenoxy]phenol | HCID 12940613 | — |
| 반응물 | Methyl 4-bromo-3-methoxypent-2-enoate | HCID 54279858 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-[4-(2-Chloro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoic acid | HCID 53860348 | — |
반응 단계
A mixture of 4-(2-chloro-4-trifluoromethylphenoxy) phenol (6.9 mmol.), methyl 4-bromo-3-methoxy-2-pentenoate (8.9 mmol.) and potassium carbonate (1.5 equis.) in acetone (15 ml.) is refluxed for 48 hours. After filtration, the filtrate was concentrated and the residue chromatographed on silica gel using 20% ethylacetate/hexane to give the methyl ester of 4-[4-(2-chloro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04408076 |
| 출처 데이터셋 | uspto-grants-1983_10 |
| ORD ID | ord-493aa7b9e12743a5bfd74929eaef950c |
| 출처 메모 | uspto-grants-1983_10 |