Veratrole → 4-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

HRID 647832노트

반응식

HRID 647832 반응식
[CH2:1]([CH:3]1[CH:7]([C:8]([OH:10])=O)[NH:6][C:5](=[O:11])[NH:4]1)[CH3:2].[CH3:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[O:20][CH3:21]>>[CH3:12][O:13][C:14]1[CH:19]=[C:18]([CH:17]=[CH:16][C:15]=1[O:20][CH3:21])[C:8]([CH:7]1[CH:3]([CH2:1][CH3:2])[NH:4][C:5](=[O:11])[NH:6]1)=[O:10]

참가 물질

3

반응물 2

HCID 7043VeratroleHCID 13245335HCID 13245335, 화합물

생성물 1

HCID 132453364-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

반응 조건

온도
100 °C

실험 절차

In 100 g PPA are suspended 15.8 g 4-ethyl-2-oxoimidazolidine-5-carboxylic acid and 13.8 g 1,2-dimethoxybenzene. The mixture is rapidly stirred and heated for 5 hours at 100° C. The reaction mixture is quenched with water and the product separates as a solid. The solid is collected and washed with water and dried. Purification is effected by chromatography over silica gel.

후처리

  1. customThe reaction mixture is quenched with water
  2. customThe solid is collected
  3. washwashed with water
  4. customdried
  5. customPurification

출처 및 근거

ORD 기록
ord-fa1bad0c5c654454b1385555b3940788
출처 데이터셋
uspto-grants-1983_10
특허 번호
US04410540

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