Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dl-Phenylalanine → D-phenylalanine N-carbobenzoxy-D-aspartic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dl-Phenylalanine | HCID 994 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | (2R)-2-(((benzyloxy)carbonyl)amino)butanedioic acid | HCID 5289152 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | D-phenylalanine N-carbobenzoxy-D-aspartic acid | HCID 13714281 | 32.1% |
반응 단계
Eight grams of DL-phenylalanine and 1.2 g of sulfuric acid was suspended in 100 ml of water at 40° C. Ten grams of N-carbobenzoxy-D-aspartic acid was added to the solution over five hours, while this solution was continuously stirred. The resulting crystal was separated, washed with 10 ml of water and dried to give 5.2 g of a D-phenylalanine N-carbobenzoxy-D-aspartic acid. Analysis revealed that the optical purity of the D-phenylalnine was 98%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04610827 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-987bea95ecff469face1ae081f9f5f8e |
| 출처 메모 | uspto-grants-1986_09 |