참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dl-Phenylalanine | HCID 994 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | N-benzenesulfonyl-L-aspartic acid | HCID 10989413 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | L-phenylalanine N-benzenesulfonyl-L-aspartic acid | HCID 86740983 | 35.8% |
반응 단계
Six grams of DL-phenylalanine, 5.4 g of N-benzenesulfonyl-L-aspartic acid and 1.8 g of sulfuric acid were dissolved in 110 ml of water. While this solution was continuously stirred at 50° C., a 10% aqueous solution of caustic soda (7.3 ml) was added over five hours. The resulting crystal was separated, washed with 10 ml of water and dried to give 3.1 g of an L-phenylalanine/N-benzenesulfonyl-L-aspartic acid salt. Analysis of this salt revealed that the optical purity of the L-phenylalanine was 94%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04610827 |
|---|
| 출처 데이터셋 | uspto-grants-1986_09 |
|---|
| ORD ID | ord-c087e91160fd4e2da6eb826b5be34b36 |
|---|
| 출처 메모 | uspto-grants-1986_09 |
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