반응식
ClC1C=C(Cl)C=C(Cl)C=1NN.[C:12]([C:14](=[C:23]([CH3:35])[NH:24][NH:25][C:26]1[C:31]([Cl:32])=[CH:30][C:29]([Cl:33])=[CH:28][C:27]=1[Cl:34])[C:15]([NH:17][C:18](OCC)=[O:19])=[O:16])#[N:13]>>[C:12]([C:14]1[C:15](=[O:16])[NH:17][C:18](=[O:19])[N:24]([NH:25][C:26]2[C:31]([Cl:32])=[CH:30][C:29]([Cl:33])=[CH:28][C:27]=2[Cl:34])[C:23]=1[CH3:35])#[N:13]참가 물질
3
실험 절차
Following the method of Example 1, N-ethoxycarbonylcyanoacetamide is heated with triethyl orthoacetate and acetic anhydride to give α-cyano-β-ethoxy-β-methyl-N-ethoxycarbonylacrylamide, which in turn is reacted with 2,4,6-trichlorophenylhydrazine. The resulting compound α-cyano-β-methyl-β-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide (m.p.=183°-184°) is cyclized, yielding 5-cyano-6-methyl-1-(2,4,6-trichloroanilino)-2,4-pyrimidinedione, m.p.=>305°.
출처 및 근거
- ORD 기록
- ord-aebfeb5fb5064674a31c808ff9acdc9b
- 출처 데이터셋
- uspto-grants-1983_10
- 특허 번호
- US04411839
연결된 노트
불러오는 중…