2,2-Diethoxyethylamine → N-(4-carboethoxyphenyl)-N'-(2,2-diethoxyethyl)thiourea

HRID 64843

반응식

HRID 64843 반응식
[C:1]([C:6]1[CH:11]=[CH:10][C:9]([N:12]=[C:13]=[S:14])=[CH:8][CH:7]=1)([O:3][CH2:4][CH3:5])=[O:2].[CH2:15]([O:17][CH:18]([O:21][CH2:22][CH3:23])[CH2:19][NH2:20])[CH3:16]>C(Cl)(Cl)(Cl)Cl>[C:1]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13]([NH:20][CH2:19][CH:18]([O:21][CH2:22][CH3:23])[O:17][CH2:15][CH3:16])=[S:14])=[CH:8][CH:7]=1)([O:3][CH2:4][CH3:5])=[O:2]

참가 물질

4

반응물 2

HCID 695242,2-DiethoxyethylamineHCID 71003Ethyl 4-isothiocyanatobenzoate

생성물 1

HCID 4842498N-(4-carboethoxyphenyl)-N'-(2,2-diethoxyethyl)thiourea

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매2회

실험 절차

20 g of 4-carboethoxyphenyl isothiocyanate was dissolved in 50 ml of carbon tetrachloride, and 13 g of aminoacetaldehyde diethylacetal was dropwise added thereto in 5 minutes. Then, the resulting solution was stirred at room temperature for 1 hour. 50 ml of carbon tetrachloride was added to the reaction mixture, and crystals precipitated were collected by filtration, washed with 50 ml of carbon tetrachloride, then dried. Yield: 27.5 g (80.9 mol%).

후처리

  1. customprecipitated
  2. filtrationwere collected by filtration
  3. washwashed with 50 ml of carbon tetrachloride
  4. customdried

출처 및 근거

ORD 기록
ord-108d4e0d97fe4223bc8e99546cc1b17a
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04610954

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